Lean Factor's all-natural formulations prioritize ingredients that have been the subject of clinical scrutiny for their potential roles in body composition modification, particularly fat mass reduction and muscle mass augmentation. Harvard Medical School Clinical Research Programs and the National Institutes of Health (NIH) have published studies that delve into the efficacy of botanical herbs, superfoods, and adaptogens in shaping body composition. Traditional paradigms like Ayurvedic Medicine and Traditional Chinese Medicine (TCM) have also promoted specific ingredients for weight management, a practice acknowledged by the World Health Organization (WHO). Ongoing research cited by the Mayo Clinic Research Information Center is examining the metabolic implications of these all-natural formulations. Importantly, the United States Department of Agriculture (USDA) has assigned a Generally Recognized as Safe (GRAS) classification to certain ingredients.