Mind & Body Anti-Aging Benefits of Nicotinamide Mononucleotide (NMN)

Could one little-known compound be the secret to healthy aging?  

Many cutting-edge researchers think so.

Over the last several decades, modern medicine and public health initiatives have increased life expectancies worldwide. But this has also led to a rise in age-related complications an diseases. 

So it’s not surprising that there’s an increasing amount of research going into anti-aging solutions to increase healthspan. 

And now get this . . . 

Researchers have discovered one incredible compound that offers huge potential in resolving many of the age-related health problems we all face as we grow older. 

This compound is called NMN (nicotinamide mononucleotide), and it has gained the attention of scientists across the world. 

Studies have shown that optimal NMN levels in the body can alleviate and even reverse many age-related conditions.

But what exactly is NMN, how can it benefit you, and where do you find it?  Let’s now explore NMN and its anti-aging benefits.

NMN: the Secret to a Long and Healthy Life?

Scientists agree that NMN can actually make you look and feel younger! 

But before we talk about NMN, we have to take a step back to address the science of anti-aging and how it starts with one crucial enzyme that currently exists in your body:

NAD+ (nicotinamide adenine dinucleotide) 

NAD+ is an essential enzyme that’s crucial for various cell functions including:

• metabolism 
• DNA repair, and 
• cell growth

NAD+ is found in all living cells and is the most abundant molecule in the body after water [1]. 

Without NAD+ acting as a coenzyme in many of the body's critical processes, life would simply cease to exist.

The problem is that NAD+ levels decline with age, making low NAD+ a hallmark of aging. 

Low Levels of NAD+ Cause Age-Related Problems

Stresses on an aging body cause NAD+ molecules to be utilized more rapidly as you grow older. This results in low levels of NAD+ which are one of the major reasons for age-related health issues [1, 2].

This is where NMN comes into play. NMN works to restore NAD+ to optimum levels. 

NMN Restores NAD+ to Youthful Levels

NMN helps prevent the oxidation that hinders cell regeneration and increases the need for DNA repair. NAD+ activates proteins called sirtuins, which play a crucial role in maintaining DNA integrity and reducing oxidative stress which leads to cell death. [3] 

As a result, your cells are better able to deal with and recover from DNA-altering stressors such as UV radiation and the electromagnetic frequencies (EMF) that continually assault our bodies. 

NMN supplementation can be used to slow and alleviate outward signs of aging such as fine lines and wrinkles, dry skin, and rough skin texture. It can also reduce the impact of sun damage that causes skin aging. [1]

But the benefits of NMN are much, much more.

NMN Increases Energy at the Cellular Level

Energy levels get depleted with age because the body uses up NAD+ faster than it can replenish it. Low NAD+ levels compromise mitochondrial function. 

But since NMN enhances mitochondrial function, NMN may also prevent aging-induced diseases. Mitochondria are the energy-generators in every cell of your body, low NAD+ levels means your cells are unable to produce enough vital energy.  NMN supplementation improves mitochondrial function which increases your cells’ ability to generate energy.  

Since NAD+ is required to metabolize glucose and fatty acids into energy, increasing NMN can result in better energy metabolism as well as increased stamina and endurance.

NMN Improves Sleep Quality and Duration

There is no question that lack of deep sleep can make your body and brain age faster.  Fortunately, helping you get quality sleep is another area where NMN shines.

NAD+ levels fluctuate during the sleep-wake cycle, regulating sleep patterns and mitochondrial activity. These fluctuations decrease as you age, affecting your sleep quality and making it less restorative [5]. 

NAD+ helps repair and protect the genes that drive circadian rhythms, keeping them healthy for longer. 

Mitochondrial activity is also governed by circadian rhythms, which is why you have more energy when you first wake than you do in the evening. When your mitochondrial activity is optimal, it will have broad effects throughout the body, including better sleep. [5]

NMN supplementation can help keep your NAD+ at optimum levels in the body for a much more efficient sleep-wake cycle.

NMN Improves Cognitive Function

NAD+ depletion has been linked to a variety of age-related illnesses, from arthritis to cancer to Alzheimer's disease.   

Studies show NMN has beneficial effects on brain function and can slow or even reverse cognitive decline.(1)  Supplementing with NMN may also help you feel mentally sharper and improve your concentration and focus.  

In addition, NMN helps to maintain the blood-brain barrier, which means your brain is protected from damaging substances but still can get vital nutrients that improve brain health and overall cognitive function.

NMN Can Help Prevent Age-Related Weight Gain

NMN can also suppress age-associated weight gain by improving metabolism and reducing muscle mass decline [3]. 

Additionally, NMN can reduce the age-associated insulin resistance allowing your body cells to use glucose more effectively leading to better metabolism, fat reduction (especially the dangerous adipose fat in the abdominal region) and a decrease in age-related weight gain [4].

NMN Has Cardiovascular Benefits

Increasing NAD+ levels in the body can slow down vascular aging.   

Higher NAD+ levels protect the health and function of the cardiovascular system, lower blood pressure, reduce vascular inflammation that can result in heart attack or stroke, and restore a more youthful functioning of your arteries.[1]. 

Boost NAD+ and Protect Yourself from
Heart Disease, Dementia and Worse

As you’ve read above, NAD+ declines with age leading to DNA damage and many conditions associated with aging including heart disease, high blood pressure, insulin resistance, fatty liver disease, dementia, and cancer. 

From slowing down skin aging to keeping your brain young, having enough of the essential enzyme NAD+ can make a  major difference in your health and how fast you age.  

NMN Can Give You Remarkable Anti-Aging Protection

Cutting-edge research has shown that the unique compound NMN restores NAD+ and therefore may be the key to slowing down and possibly even reversing aging. 

So how do you get NMN?  Well, the good news is that NMN can be easily obtained through supplementation.  And fortunately, NMN is well-tolerated and safe when taken within the recommended dosage and is also safe for long-term use.

So if you are looking to support a healthy aging process, enjoy youthful energy, improve sleep quality, improve cognition, slow down brain aging and protect your overall health as you grow older, NMN may be just what you are looking for. [1]

Only the highest quality supplements contain NMN. At Lean Factor, we use the best quality and most effective forms of nutrients, including NMN in some of our wellness formulas. 

Below is Lean Factor’s popular brain-boosting supplement that contains Nicotinamide Mononucleotide (NMN):  

Limitless Mind is a natural brain-boosting nootropic supplement designed to help you think more clearly, improve your memory, increase your focus, and reduce brain fog. It's made from all-natural ingredients to provide lasting cognitive benefits. For more information about Limitless Mind, go here.

References

1. Nature Research. "Recent research into nicotinamide mononucleotide and aging."
2. Yoshino, Jun, Joseph A. Baur, and Shin-ichiro Imai. "NAD+ intermediates: the biology and therapeutic potential of NMN and NR." Cell metabolism 27.3 (2018): 513-528.
3. Poddar, Saikat Kumar, et al. "Nicotinamide mononucleotide: an exploration of diverse therapeutic applications of a potential molecule." Biomolecules 9.1 (2019): 34.
4. Mills, Kathryn F., et al. "Long-term administration of nicotinamide mononucleotide mitigates age-associated physiological decline in mice." Cell metabolism 26 (2016): 795-806.
5. Levine, Daniel C., et al. "NAD+ controls circadian reprogramming through PER2 nuclear translocation to counter aging." Molecular cell 78.5 (2020): 835-849.